9MR6

X-ray crystal structure of SAMHD1 from Rhizophagus irregularis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	HD domain-containing protein	polymer	483	57149.3	4	UniProt (A0A015K8Z8) Pfam (PF01966) Pfam (PF19276)	Rhizophagus irregularis
2	E, G, P, Q (A, D)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	4	Chemie (GTP)
3	F, J, M, R (A, B, C, D)	PYROPHOSPHATE 2-	non-polymer		176.0	4	Chemie (POP)
4	H, K, N, S (A, B, C, D)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)
5	I, L, O, T (A, B, C, D)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
6	U, V, W, X (A, B, C, D)	water	water		18.0	137	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 463 (UniProt: A0A015K8Z8)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	228597.0
Non-Polymers*	Number of molecules	16
	Total formula weight	3176.6
All*	Total formula weight	231773.7

*Water molecules are not included.