9MQI
Inactive Mu-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound #020_E1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mu-type opioid receptor | polymer | 411 | 46081.4 | 1 | UniProt (P35372) Pfam (PF00001) | Homo sapiens (human) | M-OR-1,MOR-1,Mu opiate receptor,Mu opioid receptor,MOP,hMOP |
| 2 | B (C) | Nanobody 6M | polymer | 131 | 14418.9 | 1 | synthetic construct | ||
| 3 | C (H) | NabFab Heavy Chain | polymer | 239 | 25684.5 | 1 | synthetic construct | ||
| 4 | D (L) | NabFab Light Chain | polymer | 215 | 23258.8 | 1 | synthetic construct | ||
| 5 | E (A) | methyl (1S,3R,4S,6S,8M)-2-[(1-ethyl-1H-pyrazol-4-yl)methyl]-8-(3-hydroxyphenyl)-3,4-dimethyl-2-azabicyclo[2.2.2]oct-7-ene-6-carboxylate | non-polymer | 395.5 | 1 | Chemie (A1BNM) |
Sequence modifications
A: 1 - 400 (UniProt: P35372)
| PDB | External Database | Details |
|---|---|---|
| Asp -10 | - | expression tag |
| Tyr -9 | - | expression tag |
| Lys -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Ile -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Leu 266 | Met 266 | conflict |
| Arg 271 | Lys 271 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 109443.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 395.5 | |
| All* | Total formula weight | 109839.0 |
