9MQD
Cryo-EM structure of hemagglutinin H5N1 in complex with Fab 310-12D03
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Hemagglutinin HA1 chain | polymer | 342 | 38590.1 | 3 | UniProt (A0AAX6NN08) Pfam (PF00509) UniProt (by SIFTS) (A0A8E4ZAK5) | Influenza A virus | |
| 2 | B, D, F (B, D, F) | Hemagglutinin HA2 chain | polymer | 227 | 26166.8 | 3 | UniProt (A0A5Q2MJY3) Pfam (PF00509) UniProt (by SIFTS) (A0A8K1XY81) | Influenza A virus | |
| 3 | G, H, I (H, I, J) | Heavy chain of Fab 310-12D03 | polymer | 121 | 13086.5 | 3 | Homo sapiens (human) | ||
| 4 | J, K, L (L, M, N) | Light chain of Fab 310-12D03 | polymer | 109 | 11836.2 | 3 | Homo sapiens (human) |
Sequence modifications
A, C, E: -5 - 329 (UniProt: A0AAX6NN08)
B, D, F: -1 - 173 (UniProt: A0A5Q2MJY3)
| PDB | External Database | Details |
|---|---|---|
| Phe 98 | Tyr 107 | conflict |
| Ile 199 | Thr 211 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 174 | - | expression tag |
| Gly 175 | - | expression tag |
| Tyr 176 | - | expression tag |
| Ile 177 | - | expression tag |
| Pro 178 | - | expression tag |
| Glu 179 | - | expression tag |
| Ala 180 | - | expression tag |
| Pro 181 | - | expression tag |
| Arg 182 | - | expression tag |
| Asp 183 | - | expression tag |
| Gly 184 | - | expression tag |
| Gln 185 | - | expression tag |
| Ala 186 | - | expression tag |
| Tyr 187 | - | expression tag |
| Val 188 | - | expression tag |
| Arg 189 | - | expression tag |
| Lys 190 | - | expression tag |
| Asp 191 | - | expression tag |
| Gly 192 | - | expression tag |
| Glu 193 | - | expression tag |
| Trp 194 | - | expression tag |
| Val 195 | - | expression tag |
| Leu 196 | - | expression tag |
| Leu 197 | - | expression tag |
| Ser 198 | - | expression tag |
| Thr 199 | - | expression tag |
| Phe 200 | - | expression tag |
| Leu 201 | - | expression tag |
| Gly 202 | - | expression tag |
| Ser 203 | - | expression tag |
| Gly 204 | - | expression tag |
| Leu 205 | - | expression tag |
| Asn 206 | - | expression tag |
| Asp 207 | - | expression tag |
| Ile 208 | - | expression tag |
| Phe 209 | - | expression tag |
| Glu 210 | - | expression tag |
| Ala 211 | - | expression tag |
| Gln 212 | - | expression tag |
| Lys 213 | - | expression tag |
| Ile 214 | - | expression tag |
| Glu 215 | - | expression tag |
| Trp 216 | - | expression tag |
| His 217 | - | expression tag |
| Glu 218 | - | expression tag |
| Gly 219 | - | expression tag |
| His 220 | - | expression tag |
| His 221 | - | expression tag |
| His 222 | - | expression tag |
| His 223 | - | expression tag |
| His 224 | - | expression tag |
| His 225 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 269038.7 | |
| All* | Total formula weight | 269038.7 |
