9MPO

The cryo-EM structure of the human DNA methyltransferase DNMT3A2 and DNMT3L octamer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	DNA (cytosine-5)-methyltransferase 3A	polymer	689	77914.7	6	UniProt (Q9Y6K1) Pfam (PF00855) Pfam (PF17980) Pfam (PF21255) Pfam (PF00145)	Homo sapiens (human)	Dnmt3a,DNA methyltransferase HsaIIIA,M.HsaIIIA
2	G, H, I, M, N... (A, D, E, F)	ZINC ION	non-polymer		65.4	12	Chemie (ZN)
3	J, K, L, P, T... (A, B, C, D, E...)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	6	Chemie (SAH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	467488.3
Non-Polymers*	Number of molecules	18
	Total formula weight	3091.4
All*	Total formula weight	470579.6

*Water molecules are not included.