9MOX
Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-bound partially activated state (lower strand)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Actin, alpha cardiac muscle 1 | polymer | 377 | 42064.9 | 6 | UniProt (P68033) Pfam (PF00022) | Mus musculus (house mouse) | Alpha-cardiac actin |
| 2 | G (G) | Troponin C, slow skeletal and cardiac muscles | polymer | 161 | 18437.5 | 1 | UniProt (P19123) Pfam (PF13833) Pfam (PF13499) | Mus musculus (house mouse) | TN-C |
| 3 | H (H) | Troponin I, cardiac muscle | polymer | 211 | 24308.9 | 1 | UniProt (P48787) Pfam (PF11636) Pfam (PF00992) | Mus musculus (house mouse) | Cardiac troponin I |
| 4 | I, J (I, J) | Isoform 6 of Troponin T, cardiac muscle | polymer | 288 | 34660.3 | 2 | UniProt (P45379) Pfam (PF00992) | Mus musculus (house mouse) | TnTc,Cardiac muscle troponin T,cTnT |
| 5 | K, L, M, N (K, L, M, N) | Tropomyosin alpha-1 chain | polymer | 284 | 32735.6 | 4 | UniProt (P58771) Pfam (PF00261) | Mus musculus (house mouse) | Alpha-tropomyosin,Tropomyosin-1 |
| 6 | O, Q, S, U, W... (A, B, C, D, E...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 6 | Chemie (ADP) | |||
| 7 | P, R, T, V, X... (A, B, C, D, E...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 8 | AA, BA, CA (G) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) |
Sequence modifications
I, J: 1 - 288 (UniProt: P45379)
| PDB | External Database | Details |
|---|---|---|
| Asn 79 | Ile 79 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 495398.9 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2829.3 | |
| All* | Total formula weight | 498228.1 |
