9MNS
Structure of Hepatitis C virus envelope glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody RM1-36
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (H, h) | RM1-36 Fab heavy chain | polymer | 222 | 23767.9 | 2 | Macaca mulatta (Rhesus monkey) | ||
| 2 | B, C (L, l) | RM1-36 Fab light chain | polymer | 211 | 23085.4 | 2 | Macaca mulatta (Rhesus monkey) | ||
| 3 | E, F (E, B) | Envelope glycoprotein E2 | polymer | 231 | 25681.0 | 2 | UniProt (B9V0E2) | Recombinant Hepatitis C virus HK6a/JFH-1 | |
| 4 | G, H, I, J, K... (E, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
E, B: 421 - 645 (UniProt: B9V0E2)
| PDB | External Database | Details |
|---|---|---|
| Asp 448 | Asn 448 | conflict |
| Pro 569 | Tyr 600 | conflict |
| Thr 583 | Gln 601 | conflict |
| Asp 584 | Arg 602 | conflict |
| Gly 591 | Cys 603 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 145068.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 146396.0 |
