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9MN8

Structure of the human mitochondrial transcription initiation transitional complex, TC8

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(E)
DNA-directed RNA polymerase, mitochondrialpolymer1230138818.21UniProt (O00411)
Pfam (PF14700)
Pfam (PF00940)
Homo sapiens (human)MtRPOL
2B
(N)
Non-Template Strand DNApolymer6620524.21synthetic construct
3C
(T)
Template Strand DNApolymer6620162.91GenBank (156620758)synthetic construct
4D
(R)
RNApolymer82636.71synthetic construct
5E
(E)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
6F
(E)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence modifications
T: 8 - 55 (GenBank: 156620758)
PDBExternal DatabaseDetails
Dg -10-expression tag
Dg -9-expression tag
Dc -8-expression tag
Dc -7-expression tag
Da -6-expression tag
Dc -5-expression tag
Da -4-expression tag
Da -3-expression tag
Dt -2-expression tag
Dt -1-expression tag
Dg 0-expression tag
Dg 1-expression tag
Dg 2-expression tag
Dt 3-expression tag
Dt 4-expression tag
Dt 5-expression tag
Dt 6-expression tag
Dc 7-expression tag
-Da 950deletion
Dt 42Dc 982conflict
Dt 46Dc 986conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight182142.0
Non-Polymers*Number of molecules2
Total formula weight531.5
All*Total formula weight182673.4
*Water molecules are not included.

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PDB entries from 2026-01-14

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