9MN5
Structure of the human mitochondrial open transcription initiation complex, IC0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcription factor A, mitochondrial | polymer | 246 | 29135.7 | 1 | UniProt (Q00059) Pfam (PF00505) Pfam (PF09011) | Homo sapiens (human) | mtTFA,Mitochondrial transcription factor 1,MtTF1,Transcription factor 6,TCF-6,Transcription factor 6-like 2 |
| 2 | B (B) | Dimethyladenosine transferase 2, mitochondrial | polymer | 396 | 45416.8 | 1 | UniProt (Q9H5Q4) Pfam (PF00398) | Homo sapiens (human) | Hepatitis C virus NS5A-transactivated protein 5,HCV NS5A-transactivated protein 5,Mitochondrial 12S rRNA dimethylase 2,Mitochondrial transcription factor B2,h-mtTFB,h-mtTFB2,hTFB2M,mtTFB2,S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase 2 |
| 3 | C (E) | DNA-directed RNA polymerase, mitochondrial | polymer | 1230 | 138818.2 | 1 | UniProt (O00411) Pfam (PF14700) Pfam (PF00940) | Homo sapiens (human) | MtRPOL |
| 4 | D (N) | Non-Template strand | polymer | 60 | 18717.0 | 1 | synthetic construct | ||
| 5 | E (T) | Template strand | polymer | 60 | 18201.7 | 1 | synthetic construct |
Sequence modifications
A: 0 - 245 (UniProt: Q00059)
| PDB | External Database | Details |
|---|---|---|
| Ser 48 | Cys 49 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 250289.4 | |
| All* | Total formula weight | 250289.4 |
