9MMX

M6 protein with Factor H 6-7 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Complement factor H	polymer	125	14435.3	2	UniProt (P08603) Pfam (PF00084)	Homo sapiens (human)	H factor 1
2	C, D, E, F (C, D, E, F)	M protein, serotype 6	polymer	88	9975.7	4	UniProt (P08089)	Streptococcus pyogenes JRS4
3	G, H, I (A, D)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
4	J, K, L, M, N... (A, B, C, D, E...)	water	water		18.0	98	Chemie (HOH)

Sequence modifications

A, B: 321 - 443 (UniProt: P08603)

PDB	External Database	Details
Met 319	-	initiating methionine
Gly 320	-	expression tag

C, D, E, F: 74 - 157 (UniProt: P08089)

PDB	External Database	Details
Gly 70	-	expression tag
Pro 71	-	expression tag
Gly 72	-	expression tag
Ser 73	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	68773.3
Non-Polymers*	Number of molecules	3
	Total formula weight	186.2
All*	Total formula weight	68959.5

*Water molecules are not included.