9MKE
Crystal structure of MALT1 in complex with an allosteric inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | polymer | 386 | 43772.3 | 2 | UniProt (Q9UDY8) Pfam (PF00656) Pfam (PF18703) | Homo sapiens (human) | MALT lymphoma-associated translocation,Paracaspase |
| 2 | C, D, E, F, G... (A, B) | CALCIUM ION | non-polymer | 40.1 | 12 | Chemie (CA) | |||
| 3 | AA, J, K (B, A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 3 | Chemie (PGE) | |||
| 4 | BA, CA, DA, EA, FA... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 18 | Chemie (EDO) | |||
| 5 | KA, R (B, A) | (8R,9R)-2-chloro-N-[5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3-yl]-8-methyl-8-(trifluoromethyl)-7,8-dihydro-6H-pyrazolo[1,5-a]pyrrolo[2,3-e]pyrimidine-6-carboxamide | non-polymer | 498.2 | 2 | Chemie (A1BMY) | |||
| 6 | LA, MA (A, B) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 87544.6 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 3045.2 | |
| All* | Total formula weight | 90589.8 |
