9MK7

Crystal structure of the WDR domain of WDR91 in complex with DR3634

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	WD repeat-containing protein 91	polymer	374	41064.5	1	UniProt (A4D1P6) Pfam (PF00400)	Homo sapiens (human)	WDR91
2	B (A)	(1R)-1-({(6M)-2-(methylamino)-6-[3-(pyrrolidin-1-yl)phenyl]pyrimidin-4-yl}amino)-2,3-dihydro-1H-indene-4-carbonitrile	non-polymer		410.5	1	Chemie (A1BLV)
3	C (A)	UNKNOWN ATOM OR ION	non-polymer			1	Chemie (UNX)
4	D (A)	water	water		18.0	76	Chemie (HOH)

Sequence modifications

A: 392 - 747 (UniProt: A4D1P6)

PDB	External Database	Details
Met 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag
His 380	-	expression tag
Ser 381	-	expression tag
Ser 382	-	expression tag
Gly 383	-	expression tag
Arg 384	-	expression tag
Glu 385	-	expression tag
Asn 386	-	expression tag
Leu 387	-	expression tag
Tyr 388	-	expression tag
Phe 389	-	expression tag
Gln 390	-	expression tag
Gly 391	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41064.5
Non-Polymers*	Number of molecules	2
	Total formula weight	410.5
All*	Total formula weight	41475.0

*Water molecules are not included.