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9MJM

SOS1 IN COMPLEX WITH AN INHIBITOR

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Son of sevenless homolog 1polymer48757103.31UniProt (Q07889)
Pfam (PF00618)
Pfam (PF00617)
Homo sapiens (human)SOS-1
2B
(A)
2-({(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl}amino)-3-(2-oxaspiro[3.3]heptan-6-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4(3H)-onenon-polymer448.51Chemie (A1BMD)
3C, D, E, F, G...
(A)
1,2-ETHANEDIOLnon-polymer62.16Chemie (EDO)
4I
(A)
IMIDAZOLEnon-polymer69.11Chemie (IMD)
5J
(A)
waterwater18.0294Chemie (HOH)
Sequence modifications
A: 564 - 1049 (UniProt: Q07889)
PDBExternal DatabaseDetails
Gly 563-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight57103.3
Non-Polymers*Number of molecules8
Total formula weight890.0
All*Total formula weight57993.3
*Water molecules are not included.

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PDB entries from 2025-05-28

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