9MIP
CryoEM structure of the Protein Phasphatase 2A (Aalpha-B56gamma-Calpha) holoenzyme complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | polymer | 589 | 65378.3 | 1 | UniProt (P30153) Pfam (PF02985) | Homo sapiens (human) | Medium tumor antigen-associated 61 kDa protein,PP2A subunit A isoform PR65-alpha,PP2A subunit A isoform R1-alpha |
| 2 | B (B) | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | polymer | 524 | 61144.6 | 1 | UniProt (Q13362) Pfam (PF01603) | Homo sapiens (human) | PP2A B subunit isoform B'-gamma,PP2A B subunit isoform B56-gamma,PP2A B subunit isoform PR61-gamma,PP2A B subunit isoform R5-gamma,Renal carcinoma antigen NY-REN-29 |
| 3 | C (C) | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | polymer | 309 | 35636.2 | 1 | UniProt (P67775) Pfam (PF00149) | Homo sapiens (human) | PP2A-alpha,Replication protein C,RP-C |
| 4 | D, E (C) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 162159.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 109.9 | |
| All* | Total formula weight | 162269.0 |
