9MIA

206-3G08 Fab in complex with HIV-1 GT1.1 v4.1 SOSIP Env trimer and RM20A3 Fab

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, G, M (G, J, O)	RM20A3 heavy chain Fv	polymer	125	13511.1	3		Macaca mulatta
2	B, H, N (H, K, P)	206-3G08 heavy chain Fv	polymer	121	13610.1	3		Homo sapiens
3	C, I, O (I, M, Q)	RM20A3 light chain Fv	polymer	128	13508.8	3		Macaca mulatta
4	D, J, P (L, N, R)	206-3G08 lambda chain Fv	polymer	105	10956.9	3		Homo sapiens
5	E, K, Q (A, C, E)	GT1.1 v4.1 SOSIP gp120	polymer	509	57275.5	3	Pfam (PF00516) UniProt (by SIFTS) (Q2N0S6)	Human immunodeficiency virus 1
6	F, L, R (B, D, F)	Envelope glycoprotein gp160	polymer	153	17146.5	3	UniProt (Q2N0S6) Pfam (PF00517) UniProt (by SIFTS) (D0PUM0)	Human immunodeficiency virus 1
7	S, U, W (S, U, W)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
8	T, V, X (T, V, X)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	3	In PDB GlyTouCan (G81315DD)
9	AA, AB, BA, BB, CA... (A, E, B, F, C...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	42	Chemie (NAG)

Sequence modifications

B, D, F: 512 - 664 (UniProt: Q2N0S6)

PDB	External Database	Details
Pro 559	Ile 556	conflict
Cys 605	Thr 602	conflict

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	378026.5
Branched	Number of molecules	6
	Total formula weight	3519.2
Non-Polymers*	Number of molecules	42
	Total formula weight	9290.7
All*	Total formula weight	390836.5

*Water molecules are not included.