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9MI7

Crystal Structure of ADI-64597 ((human Fab, with substituted IgG1-CH1 (HC-L128R and K147R) and substituted kappa constant domain (LC-Q124E, V133Q, and T178R))

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
ADI-64597 Fab heavy chainpolymer22223588.41Homo sapiens (human)
2B
(L)
ADI-64597 Fab light chainpolymer21423437.91Homo sapiens (human)
3C, F
(H, L)
GLYCEROLnon-polymer92.12Chemie (GOL)
4D, E, G
(H, L)
CHLORIDE IONnon-polymer35.53Chemie (CL)
5H, I
(H, L)
waterwater18.051Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight47026.3
Non-Polymers*Number of molecules5
Total formula weight290.5
All*Total formula weight47316.8
*Water molecules are not included.

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PDB entries from 2025-12-10

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