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9MHW

Human TLR8 ectodomain with small molecule agonist 9

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Toll-like receptor 8polymer80792307.81UniProt (Q9NR97)
Pfam (PF13855)
Homo sapiens (human)
2B
(B)
alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(2-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched1073.01
3C, D
(C, D)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.52
4E, F, G, H, I...
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.29Chemie (NAG)
5N
(A)
NICKEL (II) IONnon-polymer58.71Chemie (NI)
6O
(A)
(3S)-3-[(2-amino-5-{[2-methoxy-5-({[(3S)-oxolan-3-yl]amino}methyl)phenyl]methyl}-5H-pyrimido[5,4-b]indol-4-yl)amino]hexan-1-olnon-polymer518.61Chemie (A1BLT)
7P
(A)
waterwater18.0862Chemie (HOH)
Sequence modifications
A: 27 - 827 (UniProt: Q9NR97)
PDBExternal DatabaseDetails
Glu 828-expression tag
Phe 829-expression tag
Leu 830-expression tag
Val 831-expression tag
Pro 832-expression tag
Arg 833-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight92307.8
BranchedNumber of molecules3
Total formula weight2246.0
Non-Polymers*Number of molecules11
Total formula weight2568.2
All*Total formula weight97122.0
*Water molecules are not included.

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PDB entries from 2025-12-10

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