Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Toll-like receptor 7 | polymer | 817 | 94014.7 | 2 | UniProt (B3Y653) Pfam (PF13855) | Macaca mulatta (Rhesus monkey) | |
| 2 | C (C) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 3 | D, E, F (D, E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | G, H, I, J, K... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 14 | Chemie (NAG) | |||
| 5 | N, X (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | O, Y (A, B) | (3S)-3-[(2-amino-5-{[2-methoxy-5-({[(3S)-oxolan-3-yl]amino}methyl)phenyl]methyl}-5H-pyrimido[5,4-b]indol-4-yl)amino]hexan-1-ol | non-polymer | 518.6 | 2 | Chemie (A1BLT) | |||
| 7 | P, Z (A, B) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 8 | AA, BA (A, B) | water | water | 18.0 | 439 | Chemie (HOH) |
Sequence modifications
A, B: 27 - 839 (UniProt: B3Y653)
| PDB | External Database | Details |
|---|---|---|
| Arg 23 | - | expression tag |
| Ser 24 | - | expression tag |
| Pro 25 | - | expression tag |
| Trp 26 | - | expression tag |
| Gln 167 | Asn 167 | engineered mutation |
| Gln 389 | Asn 389 | engineered mutation |
| Gln 488 | Asn 488 | engineered mutation |
| Gln 799 | Asn 799 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 188029.3 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1859.7 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 4589.4 | |
| All* | Total formula weight | 194478.4 |
