9MHB
Crystal Structure of Human P38 alpha MAPK In Complex with MW01-14-064SRM
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 14 | polymer | 362 | 41560.4 | 1 | UniProt (Q16539) Pfam (PF00069) | Homo sapiens (human) | MAP kinase 14,MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSAID-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a |
| 2 | B (A) | (5P)-N,N-dimethyl-5-(naphthalen-1-yl)-6-(pyridin-4-yl)pyrazin-2-amine | non-polymer | 326.4 | 1 | Chemie (A1BLA) | |||
| 3 | C, D (A) | 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE | non-polymer | 239.2 | 2 | Chemie (GG5) | |||
| 4 | E, H (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | F (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | I (A) | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence modifications
A: 2 - 360 (UniProt: Q16539)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Ala 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41560.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1091.2 | |
| All* | Total formula weight | 42651.5 |
