9MGY
Cryo-EM structure of Human NLRP3 complex with compound 1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | NACHT, LRR and PYD domains-containing protein 3 | polymer | 1036 | 118323.5 | 1 | UniProt (Q96P20) Pfam (PF02758) Pfam (PF14484) Pfam (PF05729) Pfam (PF17779) Pfam (PF17776) Pfam (PF13516) | Homo sapiens (human) | Angiotensin/vasopressin receptor AII/AVP-like,Caterpiller protein 1.1,CLR1.1,Cold-induced autoinflammatory syndrome 1 protein,Cryopyrin,PYRIN-containing APAF1-like protein 1 |
| 2 | B (C) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 3 | C (C) | (2M)-2-(6-{[(3R)-1-methylpiperidin-3-yl]amino}pyridazin-3-yl)-5-(trifluoromethyl)phenol | non-polymer | 352.4 | 1 | Chemie (A1BLR) | |||
| 4 | D (C) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 118323.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 859.5 | |
| All* | Total formula weight | 119183.1 |
