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9MFN

Crystal Structure of ADI-64596 (human Fab, with substituted IgG1-CH1 (HC-L145Q, K147E, and S181E) and substituted kappa constant domain (LC-T129R, T178R, and T180Q))

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
ADI-64596 Fab heavy chainpolymer22223573.31Homo sapiens (human)
2B
(L)
ADI-64596 Fab light chainpolymer21423519.11Homo sapiens (human)
3C, D, F
(H, L)
BROMIDE IONnon-polymer79.93Chemie (BR)
4E, G
(H, L)
DI(HYDROXYETHYL)ETHERnon-polymer106.12Chemie (PEG)
5H, I
(H, L)
waterwater18.038Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight47092.4
Non-Polymers*Number of molecules5
Total formula weight452.0
All*Total formula weight47544.3
*Water molecules are not included.

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PDB entries from 2026-03-11

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