9MEJ

Global structure of hCXCR4 and HIV-2 gp120

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	C-X-C chemokine receptor type 4	polymer	360	40784.4	4	UniProt (P61073) Pfam (PF12109) Pfam (PF00001)	Homo sapiens (human)	CXC-R4,CXCR-4,FB22,Fusin,HM89,LCR1,Leukocyte-derived seven transmembrane domain receptor,LESTR,Lipopolysaccharide-associated protein 3,LAP-3,LPS-associated protein 3,NPYRL,Stromal cell-derived factor 1 receptor,SDF-1 receptor
2	E (E)	gp120	polymer	479	55289.4	1	UniProt (B2LT42) UniProt (by SIFTS) (P05883)	Human immunodeficiency virus 2

Sequence modifications

A, B, C, D: 1 - 352 (UniProt: P61073)

PDB	External Database	Details
Asp 353	-	expression tag
Tyr 354	-	expression tag
Lys 355	-	expression tag
Asp 356	-	expression tag
Asp 357	-	expression tag
Asp 358	-	expression tag
Asp 359	-	expression tag
Lys 360	-	expression tag

E: 21 - 499 (UniProt: B2LT42)

PDB	External Database	Details
Asp 396	Glu 398	conflict

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	218426.9
All*	Total formula weight	218426.9

*Water molecules are not included.