9MEF
Conformational flexibility in HLA-B8: peptide tuning structural and dynamical changes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MHC class I protein | polymer | 275 | 31804.9 | 1 | UniProt (A0A3G6II09) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | ARG-ALA-ARG-ALA-ARG-ALA-ARG-ALA-ARG-ALA-ARG-ALA-PHE-PRO-LYS-LYS-LYS-TYR-CYS-LEU | polymer | 20 | 2398.9 | 1 | Human immunodeficiency virus 1 | ||
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence modifications
A: 1 - 275 (UniProt: A0A3G6II09)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Cys 76 | Glu 100 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 46083.2 | |
| All* | Total formula weight | 46083.2 |
