9MED

Crystal Structure Pyrophosphate-fructose 6-phosphate 1-phosphotransferase 1 (Pfk1) from Trichomonas vaginalis (AMP/beta-D-Glucose-6-phosphate complex)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Pyrophosphate--fructose 6-phosphate 1-phosphotransferase 1	polymer	434	47625.8	4	UniProt (O61068) Pfam (PF00365)	Trichomonas vaginalis G3	6-phosphofructokinase,pyrophosphate dependent 1,PPi-dependent phosphofructokinase 1,PPi-PFK 1,Pyrophosphate-dependent 6-phosphofructose-1-kinase 1
2	E, H, L, M, N... (A, B, C, D)	PHOSPHATE ION	non-polymer		95.0	9	Chemie (PO4)
3	F, J, P, U (A, B, C, D)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	4	Chemie (AMP)
4	G (A)	PYROPHOSPHATE	non-polymer		178.0	1	Chemie (PPV)
5	I (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6	K, Q (B, C)	6-O-phosphono-beta-D-glucopyranose	non-polymer		260.1	2	Chemie (BG6)
7	O (C)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
8	W, X, Y, Z (A, B, C, D)	water	water		18.0	16	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 426 (UniProt: O61068)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	190503.2
Non-Polymers*	Number of molecules	18
	Total formula weight	3001.6
All*	Total formula weight	193504.8

*Water molecules are not included.