9ME1

hCXCR4-CXCL12 complex with 1:1 stoichiometry

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, E, F, G... (B, A, C, D, I...)	C-X-C chemokine receptor type 4	polymer	360	40784.4	8	UniProt (P61073) Pfam (PF12109) Pfam (PF00001)	Homo sapiens (human)	CXC-R4,CXCR-4,FB22,Fusin,HM89,LCR1,Leukocyte-derived seven transmembrane domain receptor,LESTR,Lipopolysaccharide-associated protein 3,LAP-3,LPS-associated protein 3,NPYRL,Stromal cell-derived factor 1 receptor,SDF-1 receptor
2	C, D, K, L, M... (N, O, P, M, J...)	Stromal cell-derived factor 1	polymer	80	9648.4	8	UniProt (P48061) Pfam (PF00048)	Homo sapiens (human)	SDF-1,hSDF-1,C-X-C motif chemokine 12,Intercrine reduced in hepatomas,IRH,hIRH,Pre-B cell growth-stimulating factor,PBSF

Sequence modifications

B, A, C, D, I, E, K, L: 1 - 352 (UniProt: P61073)

PDB	External Database	Details
Asp 353	-	expression tag
Tyr 354	-	expression tag
Lys 355	-	expression tag
Asp 356	-	expression tag
Asp 357	-	expression tag
Asp 358	-	expression tag
Asp 359	-	expression tag
Lys 360	-	expression tag

N, O, P, M, J, F, G, H: 1 - 72 (UniProt: P48061)

PDB	External Database	Details
His 73	-	expression tag
His 74	-	expression tag
His 75	-	expression tag
His 76	-	expression tag
His 77	-	expression tag
His 78	-	expression tag
His 79	-	expression tag
His 80	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	403461.9
All*	Total formula weight	403461.9

*Water molecules are not included.