9MDT

Crystal Structure Pyrophosphate-fructose 6-phosphate 1-phosphotransferase 1 (Pfk1) from Trichomonas vaginalis (ATP/Pyrophosphate complex)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Pyrophosphate--fructose 6-phosphate 1-phosphotransferase 1	polymer	434	47625.8	4	UniProt (O61068) Pfam (PF00365)	Trichomonas vaginalis G3	6-phosphofructokinase,pyrophosphate dependent 1,PPi-dependent phosphofructokinase 1,PPi-PFK 1,Pyrophosphate-dependent 6-phosphofructose-1-kinase 1
2	E, L, M (A, B)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	3	Chemie (ATP)
3	F, N, T, W (A, B, C, D)	PYROPHOSPHATE	non-polymer		178.0	4	Chemie (PPV)
4	G (A)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	1	Chemie (AMP)
5	H, I, O, P, U... (A, B, C, D)	PHOSPHATE ION	non-polymer		95.0	8	Chemie (PO4)
6	AA, J, K, Q, R... (D, A, B)	CHLORIDE ION	non-polymer		35.5	7	Chemie (CL)
7	BA, CA, DA, EA (A, B, C, D)	water	water		18.0	173	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 426 (UniProt: O61068)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	190503.2
Non-Polymers*	Number of molecules	23
	Total formula weight	3588.6
All*	Total formula weight	194091.8

*Water molecules are not included.