9MCB
Cryo-EM structure of Human UBA1-UBE2O-Ub -Recruitment state 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin-like modifier-activating enzyme 1 | polymer | 1058 | 117976.6 | 1 | UniProt (P22314) | Homo sapiens (human) | Protein A1S9,Ubiquitin-activating enzyme E1 |
| 2 | B (B) | (E3-independent) E2 ubiquitin-conjugating enzyme | polymer | 271 | 30865.4 | 1 | UniProt (Q9C0C9) | Homo sapiens (human) | E2/E3 hybrid ubiquitin-protein ligase UBE2O,Ubiquitin carrier protein O,Ubiquitin-conjugating enzyme E2 O,Ubiquitin-conjugating enzyme E2 of 230 kDa,Ubiquitin-conjugating enzyme E2-230K,Ubiquitin-protein ligase O |
| 3 | C (C) | Ubiquitin | polymer | 76 | 8576.8 | 1 | UniProt (P0CG47) | Homo sapiens (human) | |
| 4 | D (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) |
Sequence modifications
B: 928 - 1292 (UniProt: Q9C0C9)
| PDB | External Database | Details |
|---|---|---|
| - | Glu 1153 | deletion |
| - | Lys 1154 | deletion |
| - | Ala 1155 | deletion |
| - | Gln 1156 | deletion |
| - | Ala 1157 | deletion |
| - | Leu 1158 | deletion |
| - | Pro 1159 | deletion |
| - | Asn 1160 | deletion |
| - | Gly 1161 | deletion |
| - | Val 1162 | deletion |
| - | Pro 1163 | deletion |
| - | Lys 1164 | deletion |
| - | Ala 1165 | deletion |
| - | Ser 1166 | deletion |
| - | Ser 1167 | deletion |
| - | Ser 1168 | deletion |
| - | Pro 1169 | deletion |
| - | Glu 1170 | deletion |
| - | Pro 1171 | deletion |
| - | Pro 1172 | deletion |
| - | Ala 1173 | deletion |
| - | Val 1174 | deletion |
| - | Ala 1175 | deletion |
| - | Glu 1176 | deletion |
| - | Leu 1177 | deletion |
| - | Ser 1178 | deletion |
| - | Asp 1179 | deletion |
| - | Ser 1180 | deletion |
| - | Gly 1181 | deletion |
| - | Gln 1182 | deletion |
| - | Gln 1183 | deletion |
| - | Glu 1184 | deletion |
| - | Pro 1185 | deletion |
| - | Glu 1186 | deletion |
| - | Asp 1187 | deletion |
| - | Gly 1188 | deletion |
| - | Gly 1189 | deletion |
| - | Pro 1190 | deletion |
| - | Ala 1191 | deletion |
| - | Pro 1192 | deletion |
| - | Gly 1193 | deletion |
| - | Glu 1194 | deletion |
| - | Ala 1195 | deletion |
| - | Ser 1196 | deletion |
| - | Gln 1197 | deletion |
| - | Gly 1198 | deletion |
| - | Ser 1199 | deletion |
| - | Asp 1200 | deletion |
| - | Ser 1201 | deletion |
| - | Glu 1202 | deletion |
| - | Gly 1203 | deletion |
| - | Gly 1204 | deletion |
| - | Ala 1205 | deletion |
| - | Gln 1206 | deletion |
| - | Gly 1207 | deletion |
| - | Leu 1208 | deletion |
| - | Ala 1209 | deletion |
| - | Ser 1210 | deletion |
| - | Ala 1211 | deletion |
| - | Ser 1212 | deletion |
| - | Arg 1213 | deletion |
| - | Asp 1214 | deletion |
| - | His 1215 | deletion |
| - | Thr 1216 | deletion |
| - | Asp 1217 | deletion |
| - | Gln 1218 | deletion |
| - | Thr 1219 | deletion |
| - | Ser 1220 | deletion |
| - | Glu 1221 | deletion |
| - | Thr 1222 | deletion |
| - | Ala 1223 | deletion |
| - | Pro 1224 | deletion |
| - | Asp 1225 | deletion |
| - | Ala 1226 | deletion |
| - | Ser 1227 | deletion |
| - | Val 1228 | deletion |
| - | Pro 1229 | deletion |
| - | Pro 1230 | deletion |
| - | Ser 1231 | deletion |
| - | Val 1232 | deletion |
| - | Lys 1233 | deletion |
| - | Pro 1234 | deletion |
| - | Lys 1235 | deletion |
| - | Lys 1236 | deletion |
| - | Arg 1237 | deletion |
| - | Arg 1238 | deletion |
| - | Lys 1239 | deletion |
| - | Ser 1240 | deletion |
| - | Tyr 1241 | deletion |
| - | Arg 1242 | deletion |
| - | Ser 1243 | deletion |
| - | Phe 1244 | deletion |
| - | Leu 1245 | deletion |
| - | Pro 1246 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 157418.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 157766.1 |
