9MC5
Cryo-EM structure of Human UBA1-UBE2O-Ub -Transthiolation state 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin-like modifier-activating enzyme 1 | polymer | 1058 | 117976.6 | 1 | UniProt (P22314) | Homo sapiens (human) | Protein A1S9,Ubiquitin-activating enzyme E1 |
| 2 | B (B) | (E3-independent) E2 ubiquitin-conjugating enzyme | polymer | 1292 | 141554.2 | 1 | UniProt (Q9C0C9) | Homo sapiens (human) | E2/E3 hybrid ubiquitin-protein ligase UBE2O,Ubiquitin carrier protein O,Ubiquitin-conjugating enzyme E2 O,Ubiquitin-conjugating enzyme E2 of 230 kDa,Ubiquitin-conjugating enzyme E2-230K,Ubiquitin-protein ligase O |
| 3 | C (C) | Polyubiquitin-C | polymer | 77 | 8663.9 | 1 | UniProt (P0CG48) | Homo sapiens (human) | |
| 4 | D (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) |
Sequence modifications
B: 1 - 1292 (UniProt: Q9C0C9)
C: 1 - 76 (UniProt: P0CG48)
| PDB | External Database | Details |
|---|---|---|
| Phe 50 | Ser 50 | conflict |
| Ser 1207 | Gly 1207 | variant |
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 268194.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 268541.9 |
