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9MB3

Crystal structure of YTHDC1 in complex with YL-5092

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
YTH domain-containing protein 1polymer16518766.82UniProt (Q96MU7)
Pfam (PF04146)
Homo sapiens (human)Splicing factor YT521,YT521-B
2C, G
(A, B)
N-[4-(1,3-thiazol-5-yl)phenyl]-4-[2-(trifluoromethyl)phenyl]carbonyl-1H-pyrrole-2-carboxamidenon-polymer441.42Chemie (ND0)
3D, E, H, I, J
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
4F, K
(A, B)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.12Chemie (TRS)
5L, M
(A, B)
waterwater18.0375Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight37533.5
Non-Polymers*Number of molecules9
Total formula weight1607.5
All*Total formula weight39141.0
*Water molecules are not included.

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PDB entries from 2026-03-11

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