9MA7
Cryo-EM structure of EBV gp350 D123 in complex with neutralizing antibody 1A12 and 1H5 and non-neutralizing antibody 2E9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Envelope glycoprotein GP350 | polymer | 478 | 51454.0 | 1 | UniProt (P03200) | human gammaherpesvirus 4 (Epstein-Barr virus) | Membrane antigen,MA |
| 2 | B (B) | 1H5 heavy chain no-CH2CH3 | polymer | 248 | 26271.5 | 1 | Homo sapiens | ||
| 3 | C (C) | 1H5 light chain | polymer | 235 | 24930.6 | 1 | Homo sapiens | ||
| 4 | D (D) | 1A12 heavy chain no-CH2CH3 | polymer | 248 | 26621.1 | 1 | Homo sapiens | ||
| 5 | E (E) | 1A12 light chain | polymer | 233 | 24901.8 | 1 | Homo sapiens | ||
| 6 | F (F) | 2E9 heavy chain no-CH2CH3 | polymer | 245 | 25906.1 | 1 | Homo sapiens | ||
| 7 | G (G) | 2E9 light chain | polymer | 235 | 24774.5 | 1 | Homo sapiens |
Sequence modifications
A: -8 - 461 (UniProt: P03200)
| PDB | External Database | Details |
|---|---|---|
| Gln 192 | Glu 201 | conflict |
| Gly 462 | - | expression tag |
| Ser 463 | - | expression tag |
| His 464 | - | expression tag |
| His 465 | - | expression tag |
| His 466 | - | expression tag |
| His 467 | - | expression tag |
| His 468 | - | expression tag |
| His 469 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 204859.6 | |
| All* | Total formula weight | 204859.6 |
