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9M77

The activated state of human UHRF1 bound to a mononucleosome, with the finger loop ordered and linker 4 disordered.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(B, F)
Histone H4polymer10311394.42UniProt (P62799)Xenopus laevis (African clawed frog)
2B, F
(C, G)
Histone H2Apolymer13014109.42UniProt (Q6AZJ8)Xenopus laevis (African clawed frog)
3C, G
(D, H)
Histone H2B 1.1polymer12613965.32UniProt (P02281)Xenopus laevis (African clawed frog)H2B1.1
4D, J
(E, A)
Histone H3polymer13615435.12UniProt (A0A310TTQ1)Xenopus laevis (African clawed frog)
5H
(I)
DNA (144-MER)polymer14444262.21Homo sapiens
6I
(J)
Widom 601 (non-hemimethylated strand)polymer14444648.41Homo sapiens
7K
(K)
E3 ubiquitin-protein ligase UHRF1polymer79389948.11UniProt (Q96T88)Homo sapiens (human)Inverted CCAAT box-binding protein of 90 kDa,Nuclear protein 95,Nuclear zinc finger protein Np95,HuNp95,hNp95,RING finger protein 106,RING-type E3 ubiquitin transferase UHRF1,Transcription factor ICBP90,Ubiquitin-like PHD and RING finger domain-containing protein 1,hUHRF1,Ubiquitin-like-containing PHD and RING finger domains protein 1
8L, M, N
(K)
ZINC IONnon-polymer65.43Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains11
Total formula weight288667.2
Non-Polymers*Number of molecules3
Total formula weight196.2
All*Total formula weight288863.4
*Water molecules are not included.

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PDB entries from 2026-03-11

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