9M6T
Crystal structure of SARS-Cov-2 main protease H163A mutant in complex with Pomotrelvir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3C-like proteinase nsp5 | polymer | 297 | 32847.5 | 2 | UniProt (P0DTD1) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 2 | C (B) | Pomotrelvir bound form | non-polymer | 458.0 | 1 | Chemie (ZQB) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 287 | Chemie (HOH) |
Sequence modifications
A, B: 4 - 300 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 163 | His 3426 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65695.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 458.0 | |
| All* | Total formula weight | 66153.0 |
