9M40
Cryo-EM structure of the agmatine-bound zTAAR13e-Gs complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Trace amine-associated receptor 13e | polymer | 341 | 38534.2 | 1 | UniProt (Q5QNP8) | Danio rerio (zebrafish) | |
| 2 | B (A) | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | polymer | 394 | 45699.4 | 1 | UniProt (P63092) | Homo sapiens (human) | Adenylate cyclase-stimulating G alpha protein |
| 3 | C (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62873) | Homo sapiens (human) | Transducin beta chain 1 |
| 4 | D (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) | Homo sapiens (human) | G gamma-I |
| 5 | E (N) | Nb35 | polymer | 139 | 15271.9 | 1 | Lama glama | ||
| 6 | F (R) | AGMATINE | non-polymer | 130.2 | 1 | Chemie (AG2) |
Sequence modifications
A: 1 - 394 (UniProt: P63092)
| PDB | External Database | Details |
|---|---|---|
| Asn 54 | Ser 54 | conflict |
| Ala 226 | Gly 226 | conflict |
| Ala 268 | Glu 268 | conflict |
| Lys 271 | Asn 271 | conflict |
| Asp 274 | Lys 274 | conflict |
| Lys 280 | Arg 280 | conflict |
| Asp 284 | Thr 284 | conflict |
| Thr 285 | Ile 285 | conflict |
| Ser 366 | Ala 366 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 144783.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 130.2 | |
| All* | Total formula weight | 144913.8 |
