9M3U
Crystal structure of human pyruvate dehydrogenase kinase isoform 2 in complex with ATP competitive inhibitor 24
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | polymer | 362 | 41005.8 | 1 | UniProt (Q15119) | Homo sapiens (human) | Pyruvate dehydrogenase kinase isoform 2,PDH kinase 2,PDKII |
| 2 | B, C, D, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 3 | E (A) | N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE | non-polymer | 360.9 | 1 | Chemie (TF3) | |||
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | G (A) | 2-cyano-N-[(3R)-1-[(3S)-3-ethyl-7-(ethylamino)-5-fluoranyl-2-oxidanylidene-1H-indol-3-yl]piperidin-3-yl]-2-azaspiro[3.3]heptane-6-carboxamide | non-polymer | 468.6 | 1 | Chemie (A1EQJ) | |||
| 6 | I (A) | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41005.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1169.8 | |
| All* | Total formula weight | 42175.6 |
