9M3P
Crystal structure of human pyruvate dehydrogenase kinase isoform 1 in complex with ATP competitive inhibitor 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | polymer | 383 | 43788.9 | 1 | UniProt (Q15118) Pfam (PF10436) Pfam (PF02518) | Homo sapiens (human) | Pyruvate dehydrogenase kinase isoform 1,PDH kinase 1 |
| 2 | B (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 3 | C, D (A) | N-[4-(2-chloro-5-methylpyrimidin-4-yl)phenyl]-N-(4-{[(difluoroacetyl)amino]methyl}benzyl)-2,4-dihydroxybenzamide | non-polymer | 553.0 | 2 | Chemie (SZ6) | |||
| 4 | E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | H (A) | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43788.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1421.3 | |
| All* | Total formula weight | 45210.2 |
