9M1F
Crystal structure of E. coli tryptophanyl-tRNA synthetase complexed with chuangxinmycin and ATP in closed-closed state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tryptophan--tRNA ligase | polymer | 340 | 38313.7 | 2 | UniProt (E2QFN4) Pfam (PF00579) | Escherichia coli | Tryptophanyl-tRNA synthetase,TrpRS |
| 2 | C, F (A, B) | (5~{S},6~{R})-5-methyl-7-thia-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,8,10-tetraene-6-carboxylic acid | non-polymer | 233.3 | 2 | Chemie (9E0) | |||
| 3 | D, G (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 4 | E, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | H (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 558 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 334 (UniProt: E2QFN4)
| PDB | External Database | Details |
|---|---|---|
| His 335 | - | expression tag |
| His 336 | - | expression tag |
| His 337 | - | expression tag |
| His 338 | - | expression tag |
| His 339 | - | expression tag |
| His 340 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 76627.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1621.6 | |
| All* | Total formula weight | 78249.0 |
