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9M0R

Structure of neuropeptide FF receptor 1 complex with NPVF

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer36639750.31UniProt (P54311)Rattus norvegicus (Norway rat)Transducin beta chain 1
2B
(G)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer717861.11UniProt (P63212)Bos taurus (domestic cattle)G gamma-I
3C
(L)
neuropeptide VFpolymer9969.11synthetic construct
4D
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440445.11UniProt (P63096)Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
5E
(R)
Neuropeptide FF receptor 1polymer36340832.81UniProt (Q9GZQ6)Homo sapiens (human)G-protein coupled receptor 147,RFamide-related peptide receptor OT7T022
6F
(S)
scFv16polymer24726277.31synthetic construct
Sequence modifications
B: 2 - 340 (UniProt: P54311)
PDBExternal DatabaseDetails
Met -10-initiating methionine
His -9-expression tag
His -8-expression tag
His -7-expression tag
His -6-expression tag
His -5-expression tag
His -4-expression tag
Gly -3-expression tag
Ser -2-expression tag
Leu -1-expression tag
Leu 0-expression tag
Gln 1-expression tag
Gly 341-expression tag
Ser 342-expression tag
Ser 343-expression tag
Gly 344-expression tag
Gly 345-expression tag
Gly 346-expression tag
Gly 347-expression tag
Ser 348-expression tag
Gly 349-expression tag
Gly 350-expression tag
Gly 351-expression tag
Gly 352-expression tag
Ser 353-expression tag
Ser 354-expression tag
Gly 355-expression tag
A: 1 - 354 (UniProt: P63096)
PDBExternal DatabaseDetails
Ala 203Gly 203engineered mutation
Ser 326Ala 326engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight156135.7
All*Total formula weight156135.7
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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