9M0R
Structure of neuropeptide FF receptor 1 complex with NPVF
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 366 | 39750.3 | 1 | UniProt (P54311) | Rattus norvegicus (Norway rat) | Transducin beta chain 1 |
2 | B (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P63212) | Bos taurus (domestic cattle) | G gamma-I |
3 | C (L) | neuropeptide VF | polymer | 9 | 969.1 | 1 | synthetic construct | ||
4 | D (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40445.1 | 1 | UniProt (P63096) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
5 | E (R) | Neuropeptide FF receptor 1 | polymer | 363 | 40832.8 | 1 | UniProt (Q9GZQ6) | Homo sapiens (human) | G-protein coupled receptor 147,RFamide-related peptide receptor OT7T022 |
6 | F (S) | scFv16 | polymer | 247 | 26277.3 | 1 | synthetic construct |
Sequence modifications
B: 2 - 340 (UniProt: P54311)
A: 1 - 354 (UniProt: P63096)
PDB | External Database | Details |
---|---|---|
Met -10 | - | initiating methionine |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Leu -1 | - | expression tag |
Leu 0 | - | expression tag |
Gln 1 | - | expression tag |
Gly 341 | - | expression tag |
Ser 342 | - | expression tag |
Ser 343 | - | expression tag |
Gly 344 | - | expression tag |
Gly 345 | - | expression tag |
Gly 346 | - | expression tag |
Gly 347 | - | expression tag |
Ser 348 | - | expression tag |
Gly 349 | - | expression tag |
Gly 350 | - | expression tag |
Gly 351 | - | expression tag |
Gly 352 | - | expression tag |
Ser 353 | - | expression tag |
Ser 354 | - | expression tag |
Gly 355 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 203 | Gly 203 | engineered mutation |
Ser 326 | Ala 326 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 156135.7 | |
All* | Total formula weight | 156135.7 |