9M0D
Cryo-EM structure of neurotensin receptor 1 in complex with beta-arrestin 1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Soluble cytochrome b562,Neurotensin receptor type 1 | polymer | 557 | 62097.8 | 1 | UniProt (P0ABE7) UniProt (P30989) Pfam (PF00001) | Escherichia coli | Cytochrome b-562,NT-R-1,NTR1,High-affinity levocabastine-insensitive neurotensin receptor,NTRH |
| 2 | B (B) | Beta-arrestin-1 | polymer | 402 | 45224.6 | 1 | UniProt (P49407) Pfam (PF00339) Pfam (PF02752) | Homo sapiens (human) | Arrestin beta-1,Non-visual arrestin-2 |
| 3 | C (D) | Fab30 heavy chain | polymer | 260 | 27727.0 | 1 | Homo sapiens (human) | ||
| 4 | D (Q) | Fab30 light chain | polymer | 235 | 25422.5 | 1 | Homo sapiens (human) |
Sequence modifications
R: -117 - -13 (UniProt: P0ABE7)
R: 1 - 418 (UniProt: P30989)
B: 1 - 381 (UniProt: P49407)
| PDB | External Database | Details |
|---|---|---|
| Met -135 | - | initiating methionine |
| Lys -134 | - | expression tag |
| Thr -133 | - | expression tag |
| Ile -132 | - | expression tag |
| Ile -131 | - | expression tag |
| Ala -130 | - | expression tag |
| Leu -129 | - | expression tag |
| Ser -128 | - | expression tag |
| Tyr -127 | - | expression tag |
| Ile -126 | - | expression tag |
| Phe -125 | - | expression tag |
| Cys -124 | - | expression tag |
| Leu -123 | - | expression tag |
| Val -122 | - | expression tag |
| Phe -121 | - | expression tag |
| Ala -120 | - | expression tag |
| Gly -119 | - | expression tag |
| Ser -118 | - | expression tag |
| Trp -111 | Met 29 | conflict |
| Ile -16 | His 124 | conflict |
| Leu -12 | - | linker |
| Ala -11 | - | linker |
| Ser -10 | - | linker |
| Gly -9 | - | linker |
| Ser -8 | - | linker |
| Leu -7 | - | linker |
| Glu -6 | - | linker |
| Val -5 | - | linker |
| Leu -4 | - | linker |
| Phe -3 | - | linker |
| Gln -2 | - | linker |
| Gly -1 | - | linker |
| Pro 0 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 170 | Ile 170 | conflict |
| Cys 382 | - | insertion |
| Phe 382 | - | insertion |
| Asn 382 | - | insertion |
| Cys 382 | Ala 399 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | initiating methionine |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 160471.9 | |
| All* | Total formula weight | 160471.9 |
