9LZZ
Cryo-EM structure of homomeric TRPC channel with agonists, class 2
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, C, B) | Short transient receptor potential channel 5 | polymer | 773 | 89951.9 | 4 | UniProt (Q9UL62) | Homo sapiens (human) | TrpC5,Transient receptor protein 5,TRP-5,hTRP-5,hTRP5 |
| 2 | E, L, S, Z (A, D, C, B) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 4 | Chemie (PTY) | |||
| 3 | AA, F, M, T (B, A, D, C) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 4 | Chemie (POV) | |||
| 4 | BA, G, N, U (B, A, D, C) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 4 | Chemie (Y01) | |||
| 5 | CA, H, O, V (B, A, D, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 6 | DA, I, P, W (B, A, D, C) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 7 | EA, J, Q, X (B, A, D, C) | (-)-englerin A | non-polymer | 442.5 | 4 | Chemie (A1L55) | |||
| 8 | FA, K, R, Y (B, A, D, C) | 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine | non-polymer | 234.2 | 4 | Chemie (657) |
Sequence modifications
A, D, C, B: 1 - 765 (UniProt: Q9UL62)
| PDB | External Database | Details |
|---|---|---|
| Ser 766 | - | expression tag |
| Arg 767 | - | expression tag |
| Leu 768 | - | expression tag |
| Glu 769 | - | expression tag |
| Val 770 | - | expression tag |
| Leu 771 | - | expression tag |
| Phe 772 | - | expression tag |
| Gln 773 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 359807.6 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 11052.3 | |
| All* | Total formula weight | 370859.8 |
