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9LZV

Crystal structure of human glutaminyl cyclase in complex with Inhibitor M-42

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Glutaminyl-peptide cyclotransferasepolymer32937557.46UniProt (Q16769)
Pfam (PF04389)
Homo sapiens (human)Glutaminyl cyclase,QC,sQC,Glutaminyl-tRNA cyclotransferase,Glutamyl cyclase,EC
2G, I, K, M, O...
(A, B, C, D, E...)
ZINC IONnon-polymer65.46Chemie (ZN)
3H, J, L, N, P...
(A, B, C, D, E...)
3-(1H-benzimidazol-5-yl)-5-[1-[2-(3,4-dimethoxyphenyl)ethanoyl]piperidin-4-yl]oxy-1H-benzimidazol-2-onenon-polymer527.66Chemie (A1EMG)
4S, T, U, V, W...
(A, B, C, D, E...)
waterwater18.0966Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight225344.4
Non-Polymers*Number of molecules12
Total formula weight3557.9
All*Total formula weight228902.3
*Water molecules are not included.

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PDB entries from 2026-03-25

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