9LYO
Alpha SARS-CoV-2 spike protein in complex with REGN10987 Fab homologue.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, H (i, g, l) | REGN10987 Fab homologue (Light chain) | polymer | 218 | 23334.7 | 3 | Homo sapiens | ||
| 2 | B, G, I (j, h, n) | REGN10987 Fab homologue (Heavy chain) | polymer | 223 | 23792.6 | 3 | Homo sapiens | ||
| 3 | C, D, E (A, B, C) | Spike glycoprotein | polymer | 1286 | 142662.8 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 4 | AA, BA, CA, DA, EA... (U, V, W, X, Y...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 31 | In PDB GlyTouCan (G42666HT) | |||
| 5 | AB, BB, CB, DB, OA... (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) |
Sequence modifications
A, B, C: 19 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | initiating methionine |
| Glu -1 | - | expression tag |
| Thr 0 | - | expression tag |
| Asp 1 | - | expression tag |
| Thr 2 | - | expression tag |
| Leu 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Trp 6 | - | expression tag |
| Val 7 | - | expression tag |
| Leu 8 | - | expression tag |
| Leu 9 | - | expression tag |
| Leu 10 | - | expression tag |
| Trp 11 | - | expression tag |
| Val 12 | - | expression tag |
| Pro 13 | - | expression tag |
| Gly 14 | - | expression tag |
| Ser 15 | - | expression tag |
| Thr 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Asp 18 | - | expression tag |
| - | His 69 | deletion |
| - | Val 70 | deletion |
| - | Tyr 144 | deletion |
| Tyr 501 | Asn 501 | conflict |
| Asp 570 | Ala 570 | conflict |
| Gly 614 | Asp 614 | conflict |
| His 681 | Pro 681 | conflict |
| Ala 683 | Arg 683 | conflict |
| Ala 685 | Arg 685 | conflict |
| Ile 716 | Thr 716 | conflict |
| Ala 982 | Ser 982 | conflict |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
| His 1118 | Asp 1118 | conflict |
| Glu 1209 | - | expression tag |
| Phe 1210 | - | expression tag |
| Gly 1211 | - | expression tag |
| Ser 1212 | - | expression tag |
| Gly 1213 | - | expression tag |
| Gly 1214 | - | expression tag |
| Tyr 1215 | - | expression tag |
| Ile 1216 | - | expression tag |
| Pro 1217 | - | expression tag |
| Glu 1218 | - | expression tag |
| Ala 1219 | - | expression tag |
| Pro 1220 | - | expression tag |
| Arg 1221 | - | expression tag |
| Asp 1222 | - | expression tag |
| Gly 1223 | - | expression tag |
| Gln 1224 | - | expression tag |
| Ala 1225 | - | expression tag |
| Tyr 1226 | - | expression tag |
| Val 1227 | - | expression tag |
| Arg 1228 | - | expression tag |
| Lys 1229 | - | expression tag |
| Asp 1230 | - | expression tag |
| Gly 1231 | - | expression tag |
| Glu 1232 | - | expression tag |
| Trp 1233 | - | expression tag |
| Val 1234 | - | expression tag |
| Leu 1235 | - | expression tag |
| Leu 1236 | - | expression tag |
| Ser 1237 | - | expression tag |
| Thr 1238 | - | expression tag |
| Phe 1239 | - | expression tag |
| Leu 1240 | - | expression tag |
| Lys 1241 | - | expression tag |
| Gly 1242 | - | expression tag |
| Gln 1243 | - | expression tag |
| Asp 1244 | - | expression tag |
| Asn 1245 | - | expression tag |
| Ser 1246 | - | expression tag |
| Ala 1247 | - | expression tag |
| Asp 1248 | - | expression tag |
| Ile 1249 | - | expression tag |
| Gln 1250 | - | expression tag |
| His 1251 | - | expression tag |
| Ser 1252 | - | expression tag |
| Gly 1253 | - | expression tag |
| Arg 1254 | - | expression tag |
| Pro 1255 | - | expression tag |
| Leu 1256 | - | expression tag |
| Glu 1257 | - | expression tag |
| Ser 1258 | - | expression tag |
| Arg 1259 | - | expression tag |
| Gly 1260 | - | expression tag |
| Pro 1261 | - | expression tag |
| Phe 1262 | - | expression tag |
| Glu 1263 | - | expression tag |
| Gln 1264 | - | expression tag |
| Lys 1265 | - | expression tag |
| Leu 1266 | - | expression tag |
| Ile 1267 | - | expression tag |
| Ser 1268 | - | expression tag |
| Glu 1269 | - | expression tag |
| Glu 1270 | - | expression tag |
| Asp 1271 | - | expression tag |
| Leu 1272 | - | expression tag |
| Asn 1273 | - | expression tag |
| Met 1274 | - | expression tag |
| His 1275 | - | expression tag |
| Thr 1276 | - | expression tag |
| Gly 1277 | - | expression tag |
| His 1278 | - | expression tag |
| His 1279 | - | expression tag |
| His 1280 | - | expression tag |
| His 1281 | - | expression tag |
| His 1282 | - | expression tag |
| His 1283 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 569370.3 | |
| Branched | Number of molecules | 31 |
| Total formula weight | 13156.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3539.3 | |
| All* | Total formula weight | 586066.1 |
