9LUW
Enhancing Monodispersity and Thermal Stability of Human H-Ferritin for Improved Applications in Nanocarrier Systems
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ferritin heavy chain | polymer | 183 | 21095.3 | 8 | UniProt (P02794) Pfam (PF00210) | Homo sapiens (human) | Ferritin H subunit,Cell proliferation-inducing gene 15 protein |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | FE (III) ION | non-polymer | 55.8 | 14 | Chemie (FE) | |||
| 3 | AA, BA, CA, DA, W... (E, F, G, H, A...) | water | water | 18.0 | 600 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 0 - 182 (UniProt: P02794)
| PDB | External Database | Details |
|---|---|---|
| Gln 86 | Lys 87 | conflict |
| Ala 90 | Cys 91 | engineered mutation |
| Ala 102 | Cys 103 | engineered mutation |
| Ala 105 | His 106 | engineered mutation |
| Ala 116 | Glu 117 | engineered mutation |
| His 122 | Thr 123 | engineered mutation |
| Ala 130 | Cys 131 | engineered mutation |
| His 165 | Leu 166 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 168762.7 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 781.8 | |
| All* | Total formula weight | 169544.5 |
