9LTA
Crystal Structure of Compound SKLB-D18 with MAPK7 (ERK5)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Mitogen-activated protein kinase 7 | polymer | 346 | 39742.8 | 2 | UniProt (Q13164) Pfam (PF00069) | Homo sapiens (human) | MAP kinase 7,MAPK 7,Big MAP kinase 1,BMK-1,Extracellular signal-regulated kinase 5,ERK-5 |
| 2 | C, D (B, A) | 4-[5-chloranyl-2-[[3-[(dimethylamino)methyl]phenyl]amino]pyrimidin-4-yl]-~{N}-morpholin-4-yl-thiophene-2-carboxamide | non-polymer | 473.0 | 2 | Chemie (A1EKR) | |||
| 3 | E, F (B, A) | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
B, A: 48 - 393 (UniProt: Q13164)
| PDB | External Database | Details |
|---|---|---|
| Arg 72 | Ala 72 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79485.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 946.0 | |
| All* | Total formula weight | 80431.5 |
