9LRC
Cryo-EM structure of the histamine H4 receptor-Gi protein complex (Receptor focused)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Histamine H4 receptor,Genome polyprotein | polymer | 692 | 77796.9 | 1 | UniProt (Q9H3N8) UniProt (B6F2F5) Pfam (PF00001) | Homo sapiens (human) | H4R,HH4R,AXOR35,G-protein coupled receptor 105,GPRv53,Pfi-013,SP9144 |
| 2 | B (R) | HISTAMINE | non-polymer | 111.1 | 1 | Chemie (HSM) | |||
| 3 | C (R) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
R: 2 - 390 (UniProt: Q9H3N8)
R: 412 - 651 (UniProt: B6F2F5)
| PDB | External Database | Details |
|---|---|---|
| Met -32 | - | initiating methionine |
| Lys -31 | - | expression tag |
| Thr -30 | - | expression tag |
| Ile -29 | - | expression tag |
| Ile -28 | - | expression tag |
| Ala -27 | - | expression tag |
| Leu -26 | - | expression tag |
| Ser -25 | - | expression tag |
| Tyr -24 | - | expression tag |
| Ile -23 | - | expression tag |
| Phe -22 | - | expression tag |
| Cys -21 | - | expression tag |
| Leu -20 | - | expression tag |
| Val -19 | - | expression tag |
| Phe -18 | - | expression tag |
| Ala -17 | - | expression tag |
| Asp -16 | - | expression tag |
| Tyr -15 | - | expression tag |
| Lys -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Lys -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Gly 391 | - | linker |
| Gly 392 | - | linker |
| Ser 393 | - | linker |
| Gly 394 | - | linker |
| Gly 395 | - | linker |
| Gly 396 | - | linker |
| Ser 397 | - | linker |
| Gly 398 | - | linker |
| Gly 399 | - | linker |
| Ser 400 | - | linker |
| Ser 401 | - | linker |
| Gly 402 | - | linker |
| Gly 403 | - | linker |
| Gly 404 | - | linker |
| Ser 405 | - | linker |
| Leu 406 | - | linker |
| Glu 407 | - | linker |
| Val 408 | - | linker |
| Leu 409 | - | linker |
| Phe 410 | - | linker |
| Gln 411 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Pro 413 | Ser 3 | conflict |
| Lys 619 | Ala 209 | conflict |
| His 652 | - | expression tag |
| His 653 | - | expression tag |
| His 654 | - | expression tag |
| His 655 | - | expression tag |
| His 656 | - | expression tag |
| His 657 | - | expression tag |
| His 658 | - | expression tag |
| His 659 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 77796.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 111.1 | |
| All* | Total formula weight | 77908.0 |
