9LOK
The co-crystal structure of PTP1B complex with allosteric inhibitor Fumosorinone
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 299 | 34861.7 | 2 | UniProt (P18031) | Homo sapiens (human) | Protein-tyrosine phosphatase 1B,PTP-1B |
| 2 | C, D, F, G (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 3 | E, H (B) | 5-(4-hydroxyphenyl)-1,4-bis(oxidanyl)-3-[(2~{E},4~{E},6~{Z},8~{E},10~{R},12~{R})-2,8,10,12-tetramethyltetradeca-2,4,6,8-tetraenoyl]pyridin-2-one | non-polymer | 477.6 | 2 | Chemie (A1L7F) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 299 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Arg 12 | Lys 12 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69723.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1323.6 | |
| All* | Total formula weight | 71047.0 |
