9LOC

Cryo-EM structure of human FcRL5 bound to IgG-Fc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Fc receptor-like protein 5	polymer	860	94512.0	1	UniProt (Q96RD9)	Homo sapiens (human)	FcR-like protein 5,FcRL5,BXMAS1,Fc receptor homolog 5,FcRH5,Immune receptor translocation-associated protein 2
2	B, C, D, E, F... (B, C, D, E, F...)	Immunoglobulin gamma-1 heavy chain	polymer	250	28081.8	12	UniProt (P0DOX5)	Homo sapiens (human)	Immunoglobulin gamma-1 heavy chain NIE
3	N (N)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1098.0	1	In PDB GlyTouCan (G39203UC)
4	AA, O, P, Q, R... (M, A, B, C, D...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	13	Chemie (NAG)

Sequence modifications

A: 16 - 851 (UniProt: Q96RD9)

PDB	External Database	Details
His 852	-	expression tag
His 853	-	expression tag
His 854	-	expression tag
His 855	-	expression tag
His 856	-	expression tag
His 857	-	expression tag
His 858	-	expression tag
His 859	-	expression tag
Trp 860	-	expression tag
Arg 861	-	expression tag
Pro 862	-	expression tag
Leu 863	-	expression tag
Glu 864	-	expression tag
Ser 865	-	expression tag
Arg 866	-	expression tag
Val 867	-	expression tag
Asp 868	-	expression tag
Tyr 869	-	expression tag
Lys 870	-	expression tag
Asp 871	-	expression tag
Asp 872	-	expression tag
Asp 873	-	expression tag
Asp 874	-	expression tag
Lys 875	-	expression tag

B, C, D, E, F, G, H, I, J, K, L, M: 216 - 441 (UniProt: P0DOX5)

PDB	External Database	Details
Cys 309	Leu 311	conflict
Asp 442	-	expression tag
Lys 443	-	expression tag
Ser 444	-	expression tag
Thr 445	-	expression tag
Gly 446	-	expression tag
Lys 447	-	expression tag
Pro 448	-	expression tag
Thr 449	-	expression tag
Leu 450	-	expression tag
Tyr 451	-	expression tag
Asn 452	-	expression tag
Val 453	-	expression tag
Ser 454	-	expression tag
Leu 455	-	expression tag
Ile 456	-	expression tag
Met 457	-	expression tag
Ser 458	-	expression tag
Asp 459	-	expression tag
Thr 460	-	expression tag
Gly 461	-	expression tag
Gly 462	-	expression tag
Thr 463	-	expression tag
Cys 464	-	expression tag
Tyr 465	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	13
	Total formula weight	431493.2
Branched	Number of molecules	1
	Total formula weight	1098.0
Non-Polymers*	Number of molecules	13
	Total formula weight	2875.7
All*	Total formula weight	435466.9

*Water molecules are not included.