9LN6

Structure of human NLRP14-UHRF1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Maltose/maltodextrin-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 14	polymer	1506	170249.4	1	UniProt (P0AEX9) UniProt (Q86W24)	Escherichia coli K-12	MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,Nucleotide-binding oligomerization domain protein 5
2	B (B)	Maltose/maltodextrin-binding periplasmic protein,E3 ubiquitin-protein ligase UHRF1	polymer	495	55263.1	1	UniProt (P0AEX9) UniProt (Q96T88)	Escherichia coli K-12	MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,Inverted CCAAT box-binding protein of 90 kDa,Nuclear protein 95,Nuclear zinc finger protein Np95,HuNp95,hNp95,RING finger protein 106,RING-type E3 ubiquitin transferase UHRF1,Transcription factor ICBP90,Ubiquitin-like PHD and RING finger domain-containing protein 1,hUHRF1,Ubiquitin-like-containing PHD and RING finger domains protein 1

Sequence modifications

A: -393 - -28 (UniProt: P0AEX9)

PDB	External Database	Details
Met -412	-	initiating methionine
Trp -411	-	expression tag
Ser -410	-	expression tag
His -409	-	expression tag
Pro -408	-	expression tag
Gln -407	-	expression tag
Phe -406	-	expression tag
Glu -405	-	expression tag
Lys -404	-	expression tag
Asp -403	-	expression tag
Glu -402	-	expression tag
Val -401	-	expression tag
Asp -400	-	expression tag
Ala -399	-	expression tag
Gly -398	-	expression tag
Ser -397	-	expression tag
Gly -396	-	expression tag
His -395	-	expression tag
Met -394	-	expression tag
Asn -27	-	linker
Ser -26	-	linker
Ser -25	-	linker
Ser -24	-	linker
Asn -23	-	linker
Asn -22	-	linker
Asn -21	-	linker
Asn -20	-	linker
Asn -19	-	linker
Asn -18	-	linker
Asn -17	-	linker
Asn -16	-	linker
Asn -15	-	linker
Asn -14	-	linker
Leu -13	-	linker
Gly -12	-	linker
Ile -11	-	linker
Asp -10	-	linker
Leu -9	-	linker
Glu -8	-	linker
Val -7	-	linker
Leu -6	-	linker
Phe -5	-	linker
Gln -4	-	linker
Gly -3	-	linker
Pro -2	-	linker
Gly -1	-	linker
Thr 0	-	linker

A: 1 - 1093 (UniProt: Q86W24)
B: -393 - -28 (UniProt: P0AEX9)

PDB	External Database	Details
Met -416	-	initiating methionine
His -415	-	expression tag
His -414	-	expression tag
His -413	-	expression tag
His -412	-	expression tag
His -411	-	expression tag
His -410	-	expression tag
His -409	-	expression tag
His -408	-	expression tag
His -407	-	expression tag
His -406	-	expression tag
Ser -405	-	expression tag
Gly -404	-	expression tag
Asp -403	-	expression tag
Glu -402	-	expression tag
Val -401	-	expression tag
Asp -400	-	expression tag
Ala -399	-	expression tag
Gly -398	-	expression tag
Ser -397	-	expression tag
Gly -396	-	expression tag
His -395	-	expression tag
Met -394	-	expression tag
Asn -27	-	linker
Ser -26	-	linker
Ser -25	-	linker
Ser -24	-	linker
Asn -23	-	linker
Asn -22	-	linker
Asn -21	-	linker
Asn -20	-	linker
Asn -19	-	linker
Asn -18	-	linker
Asn -17	-	linker
Asn -16	-	linker
Asn -15	-	linker
Asn -14	-	linker
Leu -13	-	linker
Gly -12	-	linker
Ile -11	-	linker
Asp -10	-	linker
Leu -9	-	linker
Glu -8	-	linker
Val -7	-	linker
Leu -6	-	linker
Phe -5	-	linker
Gln -4	-	linker
Gly -3	-	linker
Pro -2	-	linker
Gly -1	-	linker
Thr 0	-	linker

B: 1 - 78 (UniProt: Q96T88)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	225512.5
All*	Total formula weight	225512.5

*Water molecules are not included.