9LMO
Cryo-EM structure of human apo inactive GPR4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Heavy chain of anti-Bril Fab | polymer | 235 | 25008.8 | 1 | Homo sapiens | ||
| 2 | B (K) | anti-Fab Nanobody | polymer | 120 | 13159.4 | 1 | synthetic construct | ||
| 3 | C (L) | Light chain of anti-Bril Fab | polymer | 216 | 23586.2 | 1 | Homo sapiens | ||
| 4 | D (R) | G-protein coupled receptor 4,Soluble cytochrome b562 | polymer | 466 | 53012.1 | 1 | UniProt (P46093) UniProt (P0ABE7) Pfam (PF00001) | Homo sapiens (human) | G-protein coupled receptor 6C.l,GPR6C.l,Cytochrome b-562 |
Sequence modifications
R: 1 - 208 (UniProt: P46093)
R: 213 - 312 (UniProt: P0ABE7)
R: 327 - 466 (UniProt: P46093)
R: 213 - 312 (UniProt: P0ABE7)
| PDB | External Database | Details |
|---|---|---|
| Trp 219 | Met 29 | conflict |
| - | Pro 67 | deletion |
| - | Pro 68 | deletion |
| - | Lys 69 | deletion |
| - | Leu 70 | deletion |
| - | Glu 71 | deletion |
| Ile 309 | His 124 | conflict |
| Leu 313 | - | linker |
| Asp 314 | - | linker |
| Trp 315 | - | linker |
| Glu 316 | - | linker |
| Arg 317 | - | linker |
| Glu 318 | - | linker |
| Arg 319 | - | linker |
| Leu 320 | - | linker |
| Lys 321 | - | linker |
| Arg 322 | - | linker |
| Leu 323 | - | linker |
| Glu 324 | - | linker |
| Arg 325 | - | linker |
| Ile 326 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Glu 209 | - | linker |
| Lys 210 | - | linker |
| Arg 211 | - | linker |
| Arg 212 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 114766.6 | |
| All* | Total formula weight | 114766.6 |
