9LME
Checkpoint regulator protein in complex with a nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CD276 antigen | polymer | 225 | 24490.2 | 2 | UniProt (Q5ZPR3) Pfam (PF07686) Pfam (PF22705) | Homo sapiens (human) | 4Ig-B7-H3,B7 homolog 3,B7-H3,Costimulatory molecule |
| 2 | C, D (C, F) | T3CL11 | polymer | 141 | 14778.4 | 2 | Lama glama | ||
| 3 | E (D) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G47477HI) | |||
| 4 | F (E) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 5 | G, H (G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 6 | AC, BC, CB, DB, DC... (C, B, F, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 39 | Chemie (EDO) | |||
| 7 | FC, K, M, S, TA... (F, A, B) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 8 | CC, GC, N, O, P... (F, A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 11 | Chemie (PEG) | |||
| 9 | W (A) | alpha-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (MAN) | |||
| 10 | AA, AB, BA, BB, CA... (A, B, F, C) | MAGNESIUM ION | non-polymer | 24.3 | 19 | Chemie (MG) | |||
| 11 | QA, RA, TB, UB, VB (A, B) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 12 | SB (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 13 | MC, NC, OC, PC (A, B, C, F) | water | water | 18.0 | 676 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 240 (UniProt: Q5ZPR3)
| PDB | External Database | Details |
|---|---|---|
| His 16 | - | expression tag |
| His 17 | - | expression tag |
| His 18 | - | expression tag |
| His 19 | - | expression tag |
| His 20 | - | expression tag |
| His 21 | - | expression tag |
| Glu 22 | - | expression tag |
| Asn 23 | - | expression tag |
| Leu 24 | - | expression tag |
| Tyr 25 | - | expression tag |
| Phe 26 | - | expression tag |
| Gln 27 | - | expression tag |
| Gly 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 78537.3 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2460.3 | |
| Non-Polymers* | Number of molecules | 82 |
| Total formula weight | 5077.8 | |
| All* | Total formula weight | 86075.5 |
