Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 2 | B (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 3 | C (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 351 | 40122.7 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 4 | D (R) | 5-hydroxytryptamine receptor 2A | polymer | 471 | 52648.9 | 1 | UniProt (P28223) Pfam (PF00001) | Homo sapiens (human) | 5-HT-2,5-HT-2A,Serotonin receptor 2A |
| 5 | E (S) | ScFv16 | polymer | 250 | 26594.7 | 1 | Mus musculus | ||
| 6 | F (R) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) | |||
| 7 | G (R) | (2~{R})-1-(4-iodanyl-2,5-dimethoxy-phenyl)propan-2-amine | non-polymer | 321.2 | 1 | Chemie (A1EK5) | |||
| 8 | H (R) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: 4 - 354 (UniProt: P63096)
| PDB | External Database | Details |
|---|---|---|
| Asn 47 | Ser 47 | engineered mutation |
| Ala 203 | Gly 203 | engineered mutation |
| Ala 245 | Glu 245 | engineered mutation |
| Ser 326 | Ala 326 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 164644.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 707.8 | |
| All* | Total formula weight | 165352.1 |
