9LK6

dimeric ZYG11B-EloB-EloC + substrate peptide GYIND

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Protein zyg-11 homolog B,Green fluorescent protein	polymer	1009	113848.2	2	UniProt (Q9C0D3) UniProt (P42212) Pfam (PF25013) Pfam (PF22964)	Homo sapiens (human)
2	B, E (B, E)	Elongin-B	polymer	137	15393.1	2	UniProt (Q15370) Pfam (PF00240)	Homo sapiens (human)	EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2
3	C, F (C, F)	Elongin-C	polymer	112	12485.1	2	UniProt (Q15369) Pfam (PF03931)	Homo sapiens (human)	EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1
4	G, H (I, G)	GLY-TYR-ILE-ASN-ASP	polymer	5	580.6	2		Severe acute respiratory syndrome coronavirus 2

Sequence modifications

A, D: 1 - 744 (UniProt: Q9C0D3)

PDB	External Database	Details
Lys 745	-	linker
Leu 746	-	linker
Gly 747	-	linker
Ser 748	-	linker
Glu 749	-	linker
Asn 750	-	linker
Leu 751	-	linker
Tyr 752	-	linker
Phe 753	-	linker
Gln 754	-	linker
Gly 755	-	linker
Gly 756	-	linker
Ser 757	-	linker
Gly 758	-	linker

A, D: 759 - 995 (UniProt: P42212)

PDB	External Database	Details
Leu 821	Phe 64	engineered mutation
Thr 822	Ser 65	engineered mutation
Arg 837	Gln 80	engineered mutation
Ser 856	Phe 99	engineered mutation
Thr 910	Met 153	engineered mutation
Ala 920	Val 163	engineered mutation
Gly 996	-	expression tag
Ser 997	-	expression tag
Gly 998	-	expression tag
His 999	-	expression tag
His 1000	-	expression tag
His 1001	-	expression tag
His 1002	-	expression tag
His 1003	-	expression tag
His 1004	-	expression tag
His 1005	-	expression tag
His 1006	-	expression tag
His 1007	-	expression tag
His 1008	-	expression tag
His 1009	-	expression tag

B, E: 1 - 118 (UniProt: Q15370)

PDB	External Database	Details
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	284614.2
All*	Total formula weight	284614.2

*Water molecules are not included.